Several diagrams and tables from review articles during the Ox-Phos Controversy serve as an occasion to assess the nature of competition in models of theory choice in science. Many models follow "Super-Bowl" principles of polar, either-or, winner-take-all competition. A significant alternative highlighted by this episode, however, is the differentiation of domains. Incommensurability and the partial divergence of overlapping domains serve both as signals and context for shifting frameworks of competition. Appropriate strategies may thus help researchers diagnose the status of competition (...) and shape their research accordingly. (shrink)

Market-based social governance schemes that establish standards of conduct for producers and traders in international supply chains aim to reduce the negative socioenvironmental effects of globalization. While studies have examined how characteristics of social governance schemes promote socially responsible producer behavior, it has not yet been examined how these same characteristics affect consumer behavior. This is a crucial omission, because without consumer demand for socially produced products, the reach of the social benefits is likely to be limited. We develop a (...) comprehensive model that links twocharacteristics of market-based social governance schemes—(1) stringency and enforcement of requirements, and (2) promotion—to two conditions required for governance schemes to generate significant social benefits: (1) socially responsible behavior of participating firms; and (2) consumer demand for socially produced products which, in turn, expands products produced according to social governance schemes, and thus, the quantity of social benefits. We discuss market-based social governance schemes in the context of fair trade coffee. (shrink)

Acupuncture, the traditional Chinese practice of needling to alleviate pain, offers a striking case where scientific accounts in two cultures, East and West, diverge sharply. Yet the Chinese comfortably embrace the apparent ontological incommensurability. Their pragmatic posture resonates with the New Experimentalism in the West--but with some provocative differences. The development of acupuncture in China (and not in the West) further suggests general research strategies in the context of discovery. My analysis also exemplifies how one might fruitfully pursue a comparative (...) philosophy of science that explores how other cultures investigate and validate their conclusions about the natural world. (shrink)

How can we establish a political/legal order that in principle does not require the human flourishing of any person or group to be given structured preference over that of any other? Addressing this question as the central problem of political philosophy,_ Norms of Liberty_ offers a new conceptual foundation for political liberalism that takes protecting liberty, understood in terms of individual negative rights, as the primary aim of the political/legal order. Rasmussen and Den Uyl argue for construing individual rights as (...) metanormative principles, directly tied to politics, that are used to establish the political/ legal conditions under which full moral conduct can take place. These they distinguish from normative principles, used to provide guidance for moral conduct within the ambit of normative ethics. This crucial distinction allows them to develop liberalism as a metanormative theory, not a guide for moral conduct. The moral universe need not be minimized or morality grounded in sentiment or contracts to support liberalism, they show. Rather, liberalism can be supported, and many of its internal tensions avoided, with an ethical framework of Aristotelian inspiration—one that understands human flourishing to be an objective, inclusive, individualized, agent-relative, social, and self-directed activity. (shrink)

This comprehensive Gandhi reader provides an essential new reference for scholars and students of his life and thought. It is the only text available that presents Gandhi's own writings, including excerpts from three of his books—An Autobiography: The Story of My Experiments with Truth, Satyagraha in South Africa, Hind Swaraj —a major pamphlet, Constructive Programme: Its Meaning and Place, and many journal articles and letters, along with a biographical sketch of his life in historical context and recent essays by highly (...) regarded scholars. (shrink)

It is a longstanding if not altogether coherent tradition of logic and rhetorical studies that an argument can be incorrect or fallacious in virtue of some ...

Traditional scholars of philosophy and religion, both East and West, often place a major emphasis on analyzing the nature of “the self.” In recent decades, there has been a renewed interest in analyzing self, but most scholars have not claimed knowledge of an ahistorical, objective, essential self free from all cultural determinants. The contributors to this volume recognize the need to contextualize specific views of self and to analyze such views in terms of the dynamic, dialectical relations between self and (...) culture.An unusual feature of this book is that all of the chapters not only focus on traditions and individuals, East and West, but include as primary emphases comparative philosophy, religion, and culture, reinforcing individual and cultural creativity. Each chapter brings specific Eastern and Western perspectives into a dynamic, comparative relation. This comparative orientation emphasizes our growing sense of interrelatedness and interdependency. Culture and Self includes many Asian and Western philosophical, religious, and cultural perspectives. Chapters focus on Vedanta, Samkhya-Yoga, and other Hindu approaches, as well as Buddhist, Confucian, Taoist and other Indian, Chinese, and Japanese perspectives. Studies present Cartesian and other dominant Western perspectives, as well as Marx, Nietzsche, Sartre, feminism, and other Western challenges to the dominant Western interpretations of culture and self.This volume will appeal to students and readers of philosophy, religious studies, Asian studies, and cultural studies. (shrink)

How do we characterize theoretical disagreement and how does this translate into strategies for practicing scientists? I integrate Kuhn’s (1962) notions of paradigms and problem-fields with Hull’s (1982,1988) concept of populational variation and Shapere’s (1974) characterization of domains in interpreting the Ox-Phos Controversy in bioenergetics (1961-1977). The analysis highlights the differences between intraparadigm disagreement (based on proposed solutions to shared problems) and interparadigm disagreement (based on the problems themselves and views of relevant domain).Kuhn (1959,1962) introduced the notion that a single, (...) uniform paradigm guides ‘normal science’. He further suggested that scientific communities undergo gestalt-like changes in research focus, implying that all disagreement is based on ‘incommensurable’ paradigms. Philosophers and historians of science concerned largely with how consensus is established (see Laudan 1984; Laudan and Laudan 1989) have found this problematic as a universal model (e.g., Lakatos and Musgrave 1970; Laudan 1977). (shrink)

This volume shows how Gandhi's thought and action-oriented approach are significant, relevant, and urgently needed for addressing major contemporary problems and concerns, including issues of violence and nonviolence, war and peace, religious conflict and dialogue, terrorism, ethics, civil disobedience, injustice, modernism and postmodernism, oppression and exploitation, and environmental destruction. Appropriate for general readers and Gandhi specialists, this volume will be of interest for those in philosophy, religion, political science, history, cultural studies, peace studies, and many other fields.

This book is an analysis of the distinctive form of reasoning, called practical reasoning by Aristotle (as opposed to theoretical reasoning), that serves to guide behaviour.

Alexander X. Douglas situates Spinoza's philosophy in its immediate historical context, and argues that much of his work was conceived with the aim of rebutting the claims of his contemporaries. In contrast to them, Spinoza argued that philosophy reveals the true nature of God, and reinterpreted the concept of God in profound and radical ways.

PrefaceList of AbbreviationsChapter One: The Mathematical Career of the Monster of MalmesburyChapter Two: The Reform of Mathematics and of the UniversitiesIdeological Origins of the DisputeChapter Three: De Corpore and the Mathematics of MaterialismChapter Four: Disputed FoundationsHobbes vs. Wallis on the Philosophy of MathematicsChapter Five: The "Modern Analytics" and the Nature of DemonstrationChapter Six: The Demise of Hobbesian GeometryChapter Seven: The Religion, Rhetoric, and Politics of Mr. Hobbes and Dr. WallisChapter Eight: Persistence in ErrorWhy Was Hobbes So Resolutely Wrong?Appendix: Selections from (...) Hobbes's Mathematical WritingsReferencesIndex Copyright © Libri GmbH. All rights reserved. (shrink)

In the 1950s–60s biochemists searched intensively for a series of high-energy molecules in the cell. Although we now believe that these molecules do not exist, biochemists claimed to have isolated or identified them on at least sixteen occasions. The episode parallels the familiar eighteenth-century case of phlogiston, in illustrating how error is not simply the loss of facts but, instead, must be actively constructed. In addition, the debates surrounding each case demonstrate how revolutionary-scale disagreement is sometimes resolved by differentiating or (...) partitioning empirical domains, rather than by replacement of one theory by another. (shrink)

Limitations of Dienes & Perner's (D&P's) theory are traced to the assumption that the higher-order thought (HOT) theory of consciousness is true. D&P claim that 18-month-old children are capable of explicitly representing factuality, from which it follows (on D&P's theory) that they are capable of explicitly representing content, attitude, and self. D&P then attempt to explain 3-year-olds' failures on tests of voluntary control such as the dimensional change card sort by suggesting that at this age children cannot represent content and (...) attitude explicitly. We provide a better levels-of-consciousness account for age-related abulic dissociations between knowledge and action. (shrink)

Argument invention is a method that can be used to help an arguer find arguments that could be used to prove a claim he needs to defend. The aim of this paper is to show how argumentation systems recently developed in artificial intelligence can be applied to the task of argument invention. One such system called Carneades is featured. Carneades can be used to analyze arguments, evaluate arguments, to make an argument diagram, and to construct arguments from a database. Using (...) some simple examples, the paper explains how Carneades works as a system of argument invention. (shrink)

Psychopathy is a personality disorder characterized by emotional deficits and a failure to inhibit impulsive behavior and is often subdivided into “primary” and “secondary” psychopathic subtypes. The maladaptive behavior related to primary psychopathy is thought to reflect constitutional “fearlessness,” while the problematic behavior related to secondary psychopathy is motivated by other factors. The fearlessness observed in psychopathy has often been interpreted as reflecting a fundamental deficit in amygdala function, and previous studies have provided support for a low-fear model of psychopathy. (...) However, many of these studies fail to use appropriate screening procedures, use liberal inclusion criteria, or have used unconventional approaches to assay amygdala function. We measured brain activity with BOLD imaging in primary and secondary psychopaths and non-psychopathic control subjects during Pavlovian fear conditioning. In contrast to the low-fear model, we observed normal fear expression in primary psychopaths. Psychopaths also displayed greater differential BOLD activity in the amygdala relative to matched controls. Inverse patterns of activity were observed in the anterior cingulate cortex (ACC) for primary versus secondary psychopaths. Primary psychopaths exhibited a pattern of activity in the dorsal and ventral ACC consistent with enhanced fear expression, while secondary psychopaths exhibited a pattern of activity in these regions consistent with fear inhibition. These results contradict the low-fear model of psychopathy and suggest that the low fear observed for psychopaths in previous studies may be specific to secondary psychopaths. (shrink)

We describe here an interdisciplinary lab science course for non-majors using the history of science as a curricular guide. Our experience with diverse instructors underscores the importance of the teachers and classroom dynamics, beyond the curriculum. Moreover, the institutional political context is central: are courses for non-majors valued and is support given to instructors to innovate? Two sample projects are profiled.

The Nature and Status of Critical Questions in Argumentation Schemes.

We describe an error type that we call the naturalizing error: an appeal to nature as a self-justified description dictating or limiting our choices in moral, economic, political, and other social contexts. Normative cultural perspectives may be subtly and subconsciously inscribed into purportedly objective descriptions of nature, often with the apparent warrant and authority of science, yet not be fully warranted by a systematic or complete consideration of the evidence. Cognitive processes may contribute further to a failure to notice the (...) lapses in scientific reasoning and justificatory warrant. By articulating this error type at a general level, we hope to raise awareness of this pervasive error type and to facilitate critiques of claims that appeal to what is “natural” as inevitable or unchangeable. (shrink)

(Pacific Philosophical Quarterly 2007) > Another look at Bar-On, Horisk and Lycan’s criticism of deflationism. I claim that their argument turns on a simple confusion about definitions and thereby fails to establish that deflationism somehow requires meaning to be explained in terms of truth conditions.

Paul Boyer shared a Nobel Prize in 1997 for his work on the mechanism of ATP synthase. His earlier work, though (which contributed indirectly to his triumph), included major errors, both experimental and theoretical. Two benchmark cases offer insight into how scientists err and how they deal with error. Boyer's work also parallels and illustrates the emergence of bioenergetics in the second half of the twentieth century, rivaling achievements in evolution and molecular biology.

The precautionary principle brings a special challenge to the practice of evidence-based public health decision-making, suggesting changes in the interpretative methods of public health used to identify causes of disease. In this paper, precautionary changes to these methods are examined: including discounting contrary evidence, reducing the number of causal criteria, weakening the rules of evidence assigned to the criteria, and altering thresholds for statistical significance. All such changes reflect the precautionary goal of earlier primary preventive intervention, i.e. acting on insufficient (...) evidence, the least amount, or minimum level, of evidence for causation. Evaluating the impact of these changes will be difficult without a careful study of how well the current methods of causal inference work, their theoretical foundations, and the ethical implications of their applications. That research program will be most productive if it is jointly developed by public health professionals trained in the ethics and philosophy and by bioethicists and philosophers trained in the theories, methods, and practice of public health. (shrink)

Investigating the concepts and material realities of energy coursing through the arts: a foundational text. This book investigates energies—in the plural, the energies embedded and embodied in everything under the sun— as they are expressed in the arts. With contributions from scholars and critics from the visual arts, art history, anthropology, music, literature, and the history of science, it offers the first multidisciplinary investigation of the concepts and material realities of energy coursing through the arts. Just as Douglas Kahn's (...) earlier books helped introduce sound as a category for study in the arts, this new volume will be a foundational volume for future explorers in a largely uncharted domain. The modern concept of energy is only two hundred years old—an abstraction grounded in extraction—but this book takes a more expansive view. It opens with a clap: the sonic energies in a ceremony of the indigenous Goolarabooloo people of Australia. Other chapters explore the energies of photography; responses of artists in the early twentieth century—including Marcel Duchamp—to scientific discoveries in electricity and electromagnetism; the aestheticization of entropy in works by Hans Haacke and Robert Smithson; free-jazz musician Milford Graves's cross-cultural engagement with music, science, and spiritualism; energy field performance; and the self-generating energy of rumor and gossip as artwork. Contributors include such leading scholars as Linda Dalrymple Henderson, John Tresch, and Caroline A. Jones. Practicing artists and students of art history will find Energies in the Arts an essential work. Contributors Susan Ballard, Jennifer Biddle, Marcus Boon, Joan Brassil, Steven Connor, Milford Graves, Daniel Hackbarth, Linda Dalrymple Henderson, Caroline A. Jones, Douglas Kahn, David Mather, Stephen Muecke, James Nisbet, Daniela Silvestrin, Michael Taussig, John Tresch, Melissa Warak. (shrink)

The multiplicity of deubiquitinating enzymes (DUBs) encoded by vertebrate genomes is partly attributable to whole genome duplication events that occurred early in chordate evolution. By surveying the literature for the largest family of DUBs (the ubiquitin-specific proteases), extensive functional redundancy for duplicated genes has been confirmed as opposed to singletons. Dramatically conflicting results have been reported for loss of function studies conducted through RNA interference as opposed to inactivating mutations, but the contradictory findings can be reconciled by a recently proposed (...) compensatory mechanism involving nonsense-mediated RNA degradation. Duplicated genes are often inactivated to become pseudogenes, and it is proposed that such is the fate of the USP15 gene of zebrafish, a commonly used model system. As it is reviewed here, these observations have implications not only for the interpretation of model system phenotypes but also for therapeutic interventions designed to target DUBs. (shrink)

Credibility in a scientific community (sensu Shapin) is a vicarious selector (sensu Campbell) for the reliability of reports by individual scientists or institutions. Similarly, images from a microscope (sensu Hacking) are vicarious selectors for studying specimens. Working at different levels, the process of indirect reasoning and checking indicates a unity to experimentalist and sociological perspectives, along with a resonance of strategies for assessing reliability. The perspective sketched here can open dialogue between philosophical and sociological interpretations of science and resolves at (...) least one tension regarding the "primary" factors by which scientists evaluate claims. (shrink)

Pharmacists, physicians, and other health care personnel practice within an integrated system of laws and regulations that influence many treatment modalities. Capitation, managed care, and other controls strain these relationships by mandating greater oversight of how health care is delivered. From a pharmacists’s perspective, any use of medication requites knowledge of three omnipresent factors: regulatory control, formularies, and economic decision making. My objective is to raise awareness of these issues as they relate to the prescription of pain medication and to (...) pain management generally.All practice-oriented drug law and regulation is based on the federal Controlled Substances Act of 1970. The Act, also known as Title II, is part of a much larger piece of legislation, the Comprehensive Drug Abuse Prevention and Control Act of 1970. CSA was enacted to regulate the manufacturing, distribution, dispensing, and delivery of drugs or substances that are subject to, or have the potential for, abuse or physical or psychological dependence. (shrink)